diff --git a/http3/server.go b/http3/server.go
index e8f0cd8ec..adc4fc861 100644
--- a/http3/server.go
+++ b/http3/server.go
@@ -7,6 +7,7 @@ import (
 	"errors"
 	"fmt"
 	"io"
+	"math"
 	"net"
 	"net/http"
 	"runtime"
@@ -22,6 +23,13 @@ import (
 	"github.com/marten-seemann/qpack"
 )
 
+func init() {
+	// Chrome compatibility mode:
+	// Chrome 87 doesn't support key updates (support was added in Chrome 88).
+	// Don't initiate key updates to avoid breaking large downloads.
+	handshake.KeyUpdateInterval = math.MaxUint64
+}
+
 // allows mocking of quic.Listen and quic.ListenAddr
 var (
 	quicListen     = quic.ListenEarly